Generate simulated evoked data

Use simulate_sparse_stc() to simulate evoked data.

# Author: Daniel Strohmeier <daniel.strohmeier@tu-ilmenau.de>
#         Alexandre Gramfort <alexandre.gramfort@inria.fr>
#
# License: BSD-3-Clause
# Copyright the MNE-Python contributors.

import matplotlib.pyplot as plt
import numpy as np

import mne
from mne.datasets import sample
from mne.simulation import simulate_evoked, simulate_sparse_stc
from mne.time_frequency import fit_iir_model_raw
from mne.viz import plot_sparse_source_estimates

print(__doc__)

Load real data as templates

data_path = sample.data_path()
meg_path = data_path / "MEG" / "sample"
raw = mne.io.read_raw_fif(meg_path / "sample_audvis_raw.fif")
proj = mne.read_proj(meg_path / "sample_audvis_ecg-proj.fif")
raw.add_proj(proj)
raw.info["bads"] = ["MEG 2443", "EEG 053"]  # mark bad channels

fwd_fname = meg_path / "sample_audvis-meg-eeg-oct-6-fwd.fif"
ave_fname = meg_path / "sample_audvis-no-filter-ave.fif"
cov_fname = meg_path / "sample_audvis-cov.fif"

fwd = mne.read_forward_solution(fwd_fname)
fwd = mne.pick_types_forward(fwd, meg=True, eeg=True, exclude=raw.info["bads"])
cov = mne.read_cov(cov_fname)
info = mne.io.read_info(ave_fname)

label_names = ["Aud-lh", "Aud-rh"]
labels = [mne.read_label(meg_path / "labels" / f"{ln}.label") for ln in label_names]

Opening raw data file /home/circleci/mne_data/MNE-sample-data/MEG/sample/sample_audvis_raw.fif...
    Read a total of 3 projection items:
        PCA-v1 (1 x 102)  idle
        PCA-v2 (1 x 102)  idle
        PCA-v3 (1 x 102)  idle
    Range : 25800 ... 192599 =     42.956 ...   320.670 secs
Ready.
    Read a total of 6 projection items:
        ECG-planar-999--0.200-0.400-PCA-01 (1 x 203)  idle
        ECG-planar-999--0.200-0.400-PCA-02 (1 x 203)  idle
        ECG-axial-999--0.200-0.400-PCA-01 (1 x 102)  idle
        ECG-axial-999--0.200-0.400-PCA-02 (1 x 102)  idle
        ECG-eeg-999--0.200-0.400-PCA-01 (1 x 59)  idle
        ECG-eeg-999--0.200-0.400-PCA-02 (1 x 59)  idle
6 projection items deactivated
Reading forward solution from /home/circleci/mne_data/MNE-sample-data/MEG/sample/sample_audvis-meg-eeg-oct-6-fwd.fif...
    Reading a source space...
    Computing patch statistics...
    Patch information added...
    Distance information added...
    [done]
    Reading a source space...
    Computing patch statistics...
    Patch information added...
    Distance information added...
    [done]
    2 source spaces read
    Desired named matrix (kind = 3523) not available
    Read MEG forward solution (7498 sources, 306 channels, free orientations)
    Desired named matrix (kind = 3523) not available
    Read EEG forward solution (7498 sources, 60 channels, free orientations)
    Forward solutions combined: MEG, EEG
    Source spaces transformed to the forward solution coordinate frame
    364 out of 366 channels remain after picking
    366 x 366 full covariance (kind = 1) found.
    Read a total of 4 projection items:
        PCA-v1 (1 x 102) active
        PCA-v2 (1 x 102) active
        PCA-v3 (1 x 102) active
        Average EEG reference (1 x 60) active
    Read a total of 4 projection items:
        PCA-v1 (1 x 102) active
        PCA-v2 (1 x 102) active
        PCA-v3 (1 x 102) active
        Average EEG reference (1 x 60) active

Generate source time courses from 2 dipoles and the corresponding evoked data

times = np.arange(300, dtype=np.float64) / raw.info["sfreq"] - 0.1
rng = np.random.RandomState(42)


def data_fun(times):
    """Generate random source time courses."""
    return (
        50e-9
        * np.sin(30.0 * times)
        * np.exp(-((times - 0.15 + 0.05 * rng.randn(1)) ** 2) / 0.01)
    )


stc = simulate_sparse_stc(
    fwd["src"],
    n_dipoles=2,
    times=times,
    random_state=42,
    labels=labels,
    data_fun=data_fun,
)

Generate noisy evoked data

picks = mne.pick_types(raw.info, meg=True, exclude="bads")
iir_filter = fit_iir_model_raw(raw, order=5, picks=picks, tmin=60, tmax=180)[1]
nave = 100  # simulate average of 100 epochs
evoked = simulate_evoked(
    fwd, stc, info, cov, nave=nave, use_cps=True, iir_filter=iir_filter
)

    Average patch normals will be employed in the rotation to the local surface coordinates....
    Converting to surface-based source orientations...
    [done]
Projecting source estimate to sensor space...
[done]
4 projection items deactivated
Created an SSP operator (subspace dimension = 4)
4 projection items activated
SSP projectors applied...

Plot

plot_sparse_source_estimates(
    fwd["src"], stc, bgcolor=(1, 1, 1), opacity=0.5, high_resolution=True
)

plt.figure()
plt.psd(evoked.data[0])

evoked.plot(time_unit="s")

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Total number of active sources: 2

Estimated memory usage: 410 MB