Generate simulated evoked data¶

Use simulate_sparse_stc() to simulate evoked data.

# Author: Daniel Strohmeier <daniel.strohmeier@tu-ilmenau.de>
#         Alexandre Gramfort <alexandre.gramfort@inria.fr>
#
# License: BSD-3-Clause

import numpy as np
import matplotlib.pyplot as plt

import mne
from mne.datasets import sample
from mne.time_frequency import fit_iir_model_raw
from mne.viz import plot_sparse_source_estimates
from mne.simulation import simulate_sparse_stc, simulate_evoked

print(__doc__)

Load real data as templates:

data_path = sample.data_path()

raw = mne.io.read_raw_fif(data_path + '/MEG/sample/sample_audvis_raw.fif')
proj = mne.read_proj(data_path + '/MEG/sample/sample_audvis_ecg-proj.fif')
raw.add_proj(proj)
raw.info['bads'] = ['MEG 2443', 'EEG 053']  # mark bad channels

fwd_fname = data_path + '/MEG/sample/sample_audvis-meg-eeg-oct-6-fwd.fif'
ave_fname = data_path + '/MEG/sample/sample_audvis-no-filter-ave.fif'
cov_fname = data_path + '/MEG/sample/sample_audvis-cov.fif'

fwd = mne.read_forward_solution(fwd_fname)
fwd = mne.pick_types_forward(fwd, meg=True, eeg=True, exclude=raw.info['bads'])
cov = mne.read_cov(cov_fname)
info = mne.io.read_info(ave_fname)

label_names = ['Aud-lh', 'Aud-rh']
labels = [mne.read_label(data_path + '/MEG/sample/labels/%s.label' % ln)
          for ln in label_names]

Out:

Opening raw data file /home/circleci/mne_data/MNE-sample-data/MEG/sample/sample_audvis_raw.fif...
    Read a total of 3 projection items:
        PCA-v1 (1 x 102)  idle
        PCA-v2 (1 x 102)  idle
        PCA-v3 (1 x 102)  idle
    Range : 25800 ... 192599 =     42.956 ...   320.670 secs
Ready.
    Read a total of 6 projection items:
        ECG-planar-999--0.200-0.400-PCA-01 (1 x 203)  idle
        ECG-planar-999--0.200-0.400-PCA-02 (1 x 203)  idle
        ECG-axial-999--0.200-0.400-PCA-01 (1 x 102)  idle
        ECG-axial-999--0.200-0.400-PCA-02 (1 x 102)  idle
        ECG-eeg-999--0.200-0.400-PCA-01 (1 x 59)  idle
        ECG-eeg-999--0.200-0.400-PCA-02 (1 x 59)  idle
6 projection items deactivated
Reading forward solution from /home/circleci/mne_data/MNE-sample-data/MEG/sample/sample_audvis-meg-eeg-oct-6-fwd.fif...
    Reading a source space...
    Computing patch statistics...
    Patch information added...
    Distance information added...
    [done]
    Reading a source space...
    Computing patch statistics...
    Patch information added...
    Distance information added...
    [done]
    2 source spaces read
    Desired named matrix (kind = 3523) not available
    Read MEG forward solution (7498 sources, 306 channels, free orientations)
    Desired named matrix (kind = 3523) not available
    Read EEG forward solution (7498 sources, 60 channels, free orientations)
    MEG and EEG forward solutions combined
    Source spaces transformed to the forward solution coordinate frame
    364 out of 366 channels remain after picking
    366 x 366 full covariance (kind = 1) found.
    Read a total of 4 projection items:
        PCA-v1 (1 x 102) active
        PCA-v2 (1 x 102) active
        PCA-v3 (1 x 102) active
        Average EEG reference (1 x 60) active
    Read a total of 4 projection items:
        PCA-v1 (1 x 102) active
        PCA-v2 (1 x 102) active
        PCA-v3 (1 x 102) active
        Average EEG reference (1 x 60) active

Generate source time courses from 2 dipoles and the correspond evoked data

times = np.arange(300, dtype=np.float64) / raw.info['sfreq'] - 0.1
rng = np.random.RandomState(42)


def data_fun(times):
    """Function to generate random source time courses"""
    return (50e-9 * np.sin(30. * times) *
            np.exp(- (times - 0.15 + 0.05 * rng.randn(1)) ** 2 / 0.01))


stc = simulate_sparse_stc(fwd['src'], n_dipoles=2, times=times,
                          random_state=42, labels=labels, data_fun=data_fun)

Generate noisy evoked data

picks = mne.pick_types(raw.info, meg=True, exclude='bads')
iir_filter = fit_iir_model_raw(raw, order=5, picks=picks, tmin=60, tmax=180)[1]
nave = 100  # simulate average of 100 epochs
evoked = simulate_evoked(fwd, stc, info, cov, nave=nave, use_cps=True,
                         iir_filter=iir_filter)

Out:

    Average patch normals will be employed in the rotation to the local surface coordinates....
    Converting to surface-based source orientations...
    [done]
Projecting source estimate to sensor space...
[done]
4 projection items deactivated
Created an SSP operator (subspace dimension = 4)
4 projection items activated
SSP projectors applied...

Plot

plot_sparse_source_estimates(fwd['src'], stc, bgcolor=(1, 1, 1),
                             opacity=0.5, high_resolution=True)

plt.figure()
plt.psd(evoked.data[0])

evoked.plot(time_unit='s')